exRNAdisease

Entry Detail

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General Information

Database ID: exR0501687 RNA Name: KMT2D RNA Type: mRNA Chromosome: chr12 Starnd: - Coordinate: Start Site(bp): 49018975 End Site(bp): 49059774 External Links: ENSG00000167548

Disease Information

Disease Name: Lung Cancer Disease Category: Cancers MeSH ID: D008175 Type: Neoplasms/Respiratory Tract Neoplasms Alias: Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung

Expression Detail

GEO ID: GSE32175 Description: Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer Experimental Design: Cancer vs Control Case Disease Type: Lung Cancer Case Disease SubType: NA Case Sample: Lung Cancer Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABHD17A chr19 1876810 1885547 - ABHD2 chr15 89087459 89202355 + ABL1 chr9 130713016 130887675 + ABL2 chr1 179099330 179229684 - AC009133.6 chr16 29812261 29820092 + ACACA chr17 37084992 37406836 - ACIN1 chr14 23058564 23095614 - ADARB1 chr21 45073853 45226560 + ADCY6 chr12 48766194 48789037 - AEN chr15 88621337 88632281 + AGPAT1 chr6 32168212 32178096 - AGPAT3 chr21 43865223 43987592 + AKT2 chr19 40230317 40285536 - AL121845.3 chr20 63708864 63739103 + AL139300.1 chr14 103562962 103685924 + ALDH3A2 chr17 19648136 19685760 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-7-5p chr19 4770700 4770723 + hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-214-3p chr1 172138816 172138837 - hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-449a chr5 55170586 55170607 - hsa-miR-497-5p chr17 7017979 7017999 - hsa-miR-508-3p chrX 147236945 147236967 - hsa-miR-654-5p chr14 101040234 101040255 + hsa-miR-296-3p chr20 58817626 58817647 - hsa-miR-423-5p chr17 30117095 30117117 + hsa-miR-541-3p chr14 101064548 101064569 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC002310.2 chr16 30572039 30583860 + AC007383.2 chr2 206084605 206086564 + AD000090.1 chr19 35557956 35581954 + AL022157.1 chrX 57121662 57127243 + AL121832.3 chr20 62402236 62405935 - AL133523.1 chr14 100207407 100238555 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22689099 Title: Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Author: Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW. Journal: Cell Mol Life Sci. 2012 Oct;69(19):3341-3350. Description: This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.