Entry Detail


General Information

Database ID:exR0502033
RNA Name:LMNB2
RNA Type:mRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):2427638End Site(bp):2456959
External Links:ENSG00000176619



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASS
chr7
122073549
122144255
-
ABI3
chr17
49210411
49223225
+
AC005258.1
chr19
2269525
2341172
+
AC008878.3
chr19
7382834
7470241
+
AC011448.1
chr19
19516227
19536076
+
AC138696.1
chr8
143247110
143276403
+
AC138811.2
chr16
18788063
18801519
-
AC138969.1
chr16
16317444
16350590
+
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTN4
chr19
38647649
38731589
+
ADAM11
chr17
44758988
44781846
+
ADD1
chr4
2843857
2930076
+
ADK
chr10
74151202
74709963
+
ADM2
chr22
50481543
50486440
+
AGAP1
chr2
235494043
236131800
+
AHCY
chr20
34280268
34311802
-
AHCYL2
chr7
129225023
129430211
+
AHSA1
chr14
77457870
77469472
+
AKAP17A
chrX
1591604
1602520
+
AKT1
chr14
104769349
104795751
-
AL021546.1
chr12
120438198
120460006
+
ALAS1
chr3
52198086
52214327
+
ALDH9A1
chr1
165662216
165698863
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4485-3p
chr11
10508277
10508296
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL022157.1
chrX
57121662
57127243
+
AL096828.3
chr20
63218041
63218502
+
AL117335.1
chr20
1888128
1894374
-
AL118516.1
chr22
46761894
46762563
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.