Entry Detail


General Information

Database ID:exR0502523
RNA Name:MCM7
RNA Type:mRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):100092728End Site(bp):100101940
External Links:ENSG00000166508



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAR2
chr20
36236459
36270918
+
AC010422.5
chr19
12664828
12669397
-
AC037459.1
chr8
22589274
22602084
+
AC073508.2
chr17
40627356
40665141
-
AC091551.1
chr18
50968019
51058144
+
AC131160.1
chr3
183815568
183884889
-
AC245033.1
chr15
82536788
82573194
-
ACADS
chr12
120725774
120740008
+
ACIN1
chr14
23058564
23095614
-
ACTN3
chr11
66546395
66563334
+
ACVR1B
chr12
51951699
51997078
+
ADAMTS1
chr21
26835755
26845409
-
ADD2
chr2
70607618
70768225
-
ADGRV1
chr5
90529344
91164437
+
ADPGK
chr15
72751369
72785846
-
AGO2
chr8
140520156
140635633
-
AHCY
chr20
34280268
34311802
-
AIF1L
chr9
131096476
131123152
+
AKT2
chr19
40230317
40285536
-
AL513165.2
chr9
37512547
37592469
-
ALDH18A1
chr10
95605941
95656711
-
ALDH9A1
chr1
165662216
165698863
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-93-5p
chr7
100093815
100093837
-
hsa-miR-25-5p
chr7
100093610
100093630
-
hsa-miR-6790-3p
chr19
6392925
6392945
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC016876.2
chr17
7581964
7584086
-
AC091493.1
chr3
16687986
16697479
-
AC091564.7
chr11
6610883
6616594
-
AC106864.1
chr4
112693047
112706810
-
AC132217.1
chr11
2129121
2129964
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.