Entry Detail


General Information

Database ID:exR0503643
RNA Name:NONO
RNA Type:mRNA
Chromosome:chrX
Starnd:+
Coordinate:
Start Site(bp):71283192End Site(bp):71301168
External Links:ENSG00000147140



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ABL1
chr9
130713016
130887675
+
AC006064.6
chr12
6556886
6607367
-
AC010422.3
chr19
12643831
12648397
-
AC011455.2
chr19
38915404
38949855
-
AC078927.1
chr12
66123917
66169985
-
ACADVL
chr17
7217125
7225266
+
ACER3
chr11
76860867
77026797
+
ACSS3
chr12
80936414
81261210
+
ACTR6
chr12
100199122
100241865
+
AGAP4
chr10
45825594
45853875
-
AHCY
chr20
34280268
34311802
-
AIF1L
chr9
131096476
131123152
+
AKT2
chr19
40230317
40285536
-
AL049779.1
chr14
67659820
67690367
-
AL133352.1
chr10
100505628
100529881
-
ALDH1B1
chr9
38392702
38398661
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-379-5p
chr14
101022071
101022091
+
hsa-miR-338-3p
chr17
81125887
81125908
-
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-941
chr20
63919551
63919573
+
hsa-miR-3654
chr7
133034860
133034878
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC023509.1
chr12
53441741
53467528
+
AC092490.1
chr12
8788253
8795789
+
AC132217.1
chr11
2129121
2129964
-
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.