exRNAdisease

Entry Detail

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General Information

Database ID: exR0503710 RNA Name: NPTX1 RNA Type: mRNA Chromosome: chr17 Starnd: - Coordinate: Start Site(bp): 80466834 End Site(bp): 80477843 External Links: ENSG00000171246

Disease Information

Disease Name: Lung Cancer Disease Category: Cancers MeSH ID: D008175 Type: Neoplasms/Respiratory Tract Neoplasms Alias: Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung

Expression Detail

GEO ID: GSE32175 Description: Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer Experimental Design: Cancer vs Control Case Disease Type: Lung Cancer Case Disease SubType: NA Case Sample: Lung Cancer Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AASS chr7 122073549 122144255 - ACACA chr17 37084992 37406836 - ACTB chr7 5527148 5563784 - ACVR1B chr12 51951699 51997078 + AHCYL2 chr7 129225023 129430211 + AKR1A1 chr1 45550543 45570049 + AKR7A2 chr1 19303965 19312146 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-92a-3p chrX 134169544 134169565 - hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-301a-3p chr17 59151149 59151171 - hsa-miR-363-3p chrX 134169382 134169403 - hsa-miR-367-3p chr4 112647877 112647898 - hsa-miR-346 chr10 86264747 86264769 - hsa-miR-449a chr5 55170586 55170607 - hsa-miR-493-3p chr14 100869116 100869137 + hsa-miR-92b-3p chr1 155195237 155195258 + hsa-miR-449b-5p chr5 55170706 55170727 - hsa-miR-1224-5p chr3 184241405 184241423 + hsa-miR-1286 chr22 20249145 20249165 - hsa-miR-6818-3p chr22 30007092 30007113 + circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22689099 Title: Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Author: Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW. Journal: Cell Mol Life Sci. 2012 Oct;69(19):3341-3350. Description: This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.