Entry Detail


General Information

Database ID:exR0503830
RNA Name:NUCKS1
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):205712822End Site(bp):205750182
External Links:ENSG00000069275



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ALDOA
chr16
30064164
30070457
+
AFAP1
chr4
7758714
7939926
-
AC068946.2
chr2
219209772
219222738
-
AC015813.2
chr17
57989038
58007246
-
AC091959.3
chr5
146203550
146339251
+
ACTR3
chr2
113890063
113962596
+
AC005832.4
chr12
4604944
4662643
+
ACSS2
chr20
34872146
34927962
+
AC120057.2
chr17
7240427
7244635
-
AGPAT3
chr21
43865223
43987592
+
AC092143.1
chr16
89919165
89936092
+
ALDH7A1
chr5
126531200
126595362
-
ABRACL
chr6
139028745
139043302
+
ABCC1
chr16
15949577
16143074
+
AGPAT1
chr6
32168212
32178096
-
AC010422.3
chr19
12643831
12648397
-
AC058822.1
chr4
53377839
54295272
+
AL136454.1
chr1
192716132
192716653
+
AC020915.5
chr19
58228914
58315183
+
ACTR1A
chr10
102461881
102502712
-
ADAR
chr1
154582057
154628013
-
AKT2
chr19
40230317
40285536
-
AL121594.1
chr14
35122549
35317474
+
ACSL4
chrX
109624244
109733403
-
AC010463.1
chr19
17267418
17282966
+
AFF4
chr5
132875395
132963634
-
AGL
chr1
99850361
99924023
+
AIMP2
chr7
6009255
6023834
+
AHSP
chr16
31527900
31528803
+
AC008982.1
chr19
38817471
38840178
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-671-5p
chr7
151238449
151238471
+
hsa-miR-4426
chr1
192716333
192716349
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005005.3
chr22
31082156
31083565
-
AC005899.4
chr17
32328441
32329395
+
AC012368.1
chr2
64143239
64252859
+
AC015522.1
chr8
83912713
84142463
+
AC022784.3
chr8
9255349
9260295
-
AC069281.2
chr7
100572232
100578700
-
AC132217.1
chr11
2129121
2129964
-
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.