Entry Detail


General Information

Database ID:exR0504443
RNA Name:PDIA6
RNA Type:mRNA
Chromosome:chr2
Starnd:-
Coordinate:
Start Site(bp):10783391End Site(bp):10837977
External Links:ENSG00000143870



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAGAB
chr15
67200667
67255195
-
AC008982.1
chr19
38817471
38840178
-
AC010132.3
chr7
42909273
42932174
-
AC015813.2
chr17
57989038
58007246
-
AC018523.2
chr11
14493783
14520344
-
AC046185.1
chr17
63702845
63752097
-
AC079447.1
chr2
99141485
99322741
+
AC087289.3
chr17
75898645
75930129
-
AC092587.1
chr2
99154998
99195298
+
AC138894.1
chr16
28456371
28492098
-
ACLY
chr17
41866917
41930542
-
ACTG1
chr17
81509971
81523847
-
AGRN
chr1
1020120
1056118
+
AHCYL1
chr1
109984765
110023742
+
AIDA
chr1
222668013
222713210
-
AL136295.5
chr14
24147548
24166452
+
AL136454.1
chr1
192716132
192716653
+
AL645941.2
chr6
32937364
32953122
-
ALDH9A1
chr1
165662216
165698863
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4426
chr1
192716333
192716349
+
hsa-miR-4700-5p
chr12
120723202
120723223
+
hsa-miR-4700-3p
chr12
120723233
120723258
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016876.2
chr17
7581964
7584086
-
AC245014.3
chr1
145281116
145281462
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.