Entry Detail


General Information

Database ID:exR0504537
RNA Name:PFN1
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):4945652End Site(bp):4949061
External Links:ENSG00000108518



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AFAP1
chr4
7758714
7939926
-
ADGRA3
chr4
22345071
22516066
-
AGFG1
chr2
227472152
227561214
+
AJM1
chr9
136844415
136848801
+
ADD1
chr4
2843857
2930076
+
AC099489.1
chr16
11359845
11527245
-
AL139011.2
chr1
160216800
160285130
-
ACOX2
chr3
58505136
58537283
-
AC139530.2
chr17
81703371
81720539
+
AC104109.3
chr5
134167170
134226071
-
AC099811.2
chr17
42119674
42154916
-
AC092143.1
chr16
89919165
89936092
+
ALDOA
chr16
30064164
30070457
+
ACSS2
chr20
34872146
34927962
+
ABCD4
chr14
74285269
74303055
-
AGA
chr4
177430774
177442437
-
AC073508.2
chr17
40627356
40665141
-
AIFM1
chrX
130129362
130165887
-
AL121594.1
chr14
35122549
35317474
+
AC005258.1
chr19
2269525
2341172
+
AGRN
chr1
1020120
1056118
+
AGPAT5
chr8
6708642
6761503
+
ABCG2
chr4
88090150
88231628
-
ACTA1
chr1
229431245
229434098
-
ADAM10
chr15
58588809
58749791
-
AGPAT1
chr6
32168212
32178096
-
AHCY
chr20
34280268
34311802
-
ACTB
chr7
5527148
5563784
-
AC004922.1
chr7
99325879
99394653
+
AC008763.3
chr19
7678501
7682854
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-320a-3p
chr8
22244975
22244996
-
hsa-miR-330-3p
chr19
45639009
45639031
-
hsa-miR-320b
chr1
224257049
224257070
-
hsa-miR-320c
chr18
24321716
24321735
+
hsa-miR-320d
chr13
40727828
40727846
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004687.1
chr17
58330884
58332508
-
AC016876.2
chr17
7581964
7584086
-
AC020663.1
chr16
4730115
4752565
-
AC022031.2
chr18
55589904
55839184
+
AC023509.1
chr12
53441741
53467528
+
AC026362.1
chr12
122975320
122982907
+
AC060780.1
chr17
43148368
43171037
-
AC109460.3
chr16
28974804
28990775
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL023653.1
chrX
129794994
129796963
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.