Entry Detail


General Information

Database ID:exR0504578
RNA Name:PHB2
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):6965327End Site(bp):6970753
External Links:ENSG00000215021



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
ABL1
chr9
130713016
130887675
+
ABT1
chr6
26596953
26600739
+
AC004832.3
chr22
30409255
30428990
+
AC006064.6
chr12
6556886
6607367
-
AC007192.1
chr19
18153158
18178117
+
AC010422.3
chr19
12643831
12648397
-
AC011511.1
chr19
10305427
10316009
-
AC093525.1
chr16
2513965
2527955
+
AC245033.1
chr15
82536788
82573194
-
ACAT1
chr11
108116695
108147603
+
ACIN1
chr14
23058564
23095614
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ACTN4
chr19
38647649
38731589
+
ADAR
chr1
154582057
154628013
-
ADCY1
chr7
45574140
45723116
+
ADCY2
chr5
7396138
7830081
+
ADCY3
chr2
24819169
24919839
-
ADD2
chr2
70607618
70768225
-
ADGRL2
chr1
81306160
81992436
+
ADNP2
chr18
80109262
80147523
+
AHRR
chr5
271670
438291
+
AL021546.1
chr12
120438198
120460006
+
ALAS1
chr3
52198086
52214327
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-491-5p
chr9
20716120
20716141
+
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-744-5p
chr17
12081909
12081930
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002116.1
chr19
36008638
36014235
-
AC006064.5
chr12
6510275
6510522
+
AC010642.2
chr19
58309727
58327248
-
AC016876.2
chr17
7581964
7584086
-
AC023509.1
chr12
53441741
53467528
+
AC091564.7
chr11
6610883
6616594
-
AC139149.1
chr17
81514047
81527776
+
AC245033.4
chr15
82533175
82540008
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.