exRNAdisease

Entry Detail

---



General Information

Database ID: exR0504581 RNA Name: PHC3 RNA Type: mRNA Chromosome: chr3 Starnd: - Coordinate: Start Site(bp): 170086732 End Site(bp): 170181749 External Links: ENSG00000173889

Disease Information

Disease Name: Lung Cancer Disease Category: Cancers MeSH ID: D008175 Type: Neoplasms/Respiratory Tract Neoplasms Alias: Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung

Expression Detail

GEO ID: GSE32175 Description: Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer Experimental Design: Cancer vs Control Case Disease Type: Lung Cancer Case Disease SubType: NA Case Sample: Lung Cancer Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AAMP chr2 218264123 218270257 - ABR chr17 1003518 1229738 - ABTB2 chr11 34150987 34358010 - ACSS1 chr20 25006230 25058980 - ADD3 chr10 109996368 110135565 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7a-5p chr9 94175962 94175983 + hsa-let-7b-5p chr22 46113691 46113712 + hsa-let-7d-5p chr9 94178841 94178862 + hsa-let-7e-5p chr19 51692793 51692814 + hsa-let-7f-5p chrX 53557246 53557267 - hsa-let-7g-5p chr3 52268336 52268357 - hsa-let-7i-5p chr12 62603691 62603712 + hsa-miR-150-5p chr19 49500832 49500853 - hsa-miR-373-3p chr19 53788748 53788770 + hsa-miR-432-5p chr14 100884496 100884518 + hsa-miR-520e-3p chr19 53675764 53675784 + hsa-miR-520a-3p chr19 53690933 53690954 + hsa-miR-520b-3p chr19 53701267 53701287 + hsa-miR-520c-3p chr19 53707506 53707527 + hsa-miR-520d-3p chr19 53720149 53720170 + hsa-miR-488-3p chr1 177029374 177029394 - hsa-miR-532-3p chrX 50003204 50003225 + hsa-miR-873-5p chr9 28888925 28888945 - circRNA targets: NA lncRNA targets: NA Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22689099 Title: Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Author: Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW. Journal: Cell Mol Life Sci. 2012 Oct;69(19):3341-3350. Description: This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.