Entry Detail


General Information

Database ID:exR0504739
RNA Name:PKM
RNA Type:mRNA
Chromosome:chr15
Starnd:-
Coordinate:
Start Site(bp):72199029End Site(bp):72231822
External Links:ENSG00000067225



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASDHPPT
chr11
106075501
106098699
+
AC027796.3
chr17
3585149
3636249
-
AC091167.2
chr15
90249556
90272208
+
ACACB
chr12
109116595
109268226
+
AL136454.1
chr1
192716132
192716653
+
AC093525.2
chr16
2496032
2520218
+
AL121594.1
chr14
35122549
35317474
+
AHCY
chr20
34280268
34311802
-
ACADM
chr1
75724347
75787575
+
ADA
chr20
44619522
44652233
-
AKT1S1
chr19
49869033
49878459
-
ADAR
chr1
154582057
154628013
-
ACTG2
chr2
73892314
73919865
+
AASS
chr7
122073549
122144255
-
AL121753.1
chr20
35267885
35280043
-
ADAM22
chr7
87934143
88202889
+
AHNAK
chr11
62433542
62556235
-
ADPGK
chr15
72751369
72785846
-
AC011448.1
chr19
19516227
19536076
+
ACO2
chr22
41469117
41528989
+
AC011462.1
chr19
41350853
41425001
+
AC093323.1
chr4
6663396
6676755
+
AD000671.2
chr19
35739252
35745432
-
ACTG1
chr17
81509971
81523847
-
ACTC1
chr15
34790230
34795549
-
ACAT2
chr6
159762045
159779112
+
AL133352.1
chr10
100505628
100529881
-
AIP
chr11
67483026
67491103
+
AC010422.3
chr19
12643831
12648397
-
AF241726.2
chrX
37349330
38687674
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-367-3p
chr4
112647877
112647898
-
hsa-miR-654-5p
chr14
101040234
101040255
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-1286
chr22
20249145
20249165
-
hsa-miR-3610
chr8
116874740
116874759
-
hsa-miR-5587-5p
chr16
535316
535333
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005899.4
chr17
32328441
32329395
+
AC010327.5
chr19
55216660
55221616
+
AC016876.2
chr17
7581964
7584086
-
AC020663.1
chr16
4730115
4752565
-
AC020928.1
chr19
36773112
36777078
+
AC024940.6
chr12
31280422
31280895
-
AC068205.2
chr11
43578889
43840030
+
AC079781.5
chr7
97851688
97972985
-
AC093827.4
chr4
86924630
86936202
-
AC100861.1
chr8
23224471
23230926
+
AC104461.1
chr1
200333193
200478669
+
AC106875.1
chr2
11681460
11683328
+
AC109460.3
chr16
28974804
28990775
+
AC132217.1
chr11
2129121
2129964
-
AC135048.1
chr16
30948386
30956511
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
AL031282.2
chr1
1702736
1737688
-
AL049796.1
chr1
93847174
93848939
+
AL110115.2
chr20
31580890
31581214
+
AL121992.1
chr1
15586136
15603626
-
AL137058.2
chr13
52600042
52642542
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.