exRNAdisease

Entry Detail

---



General Information

Database ID: exR0504775 RNA Name: PLAGL2 RNA Type: mRNA Chromosome: chr20 Starnd: - Coordinate: Start Site(bp): 32192504 End Site(bp): 32207743 External Links: ENSG00000126003

Disease Information

Disease Name: Lung Cancer Disease Category: Cancers MeSH ID: D008175 Type: Neoplasms/Respiratory Tract Neoplasms Alias: Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung

Expression Detail

GEO ID: GSE32175 Description: Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer Experimental Design: Cancer vs Control Case Disease Type: Lung Cancer Case Disease SubType: NA Case Sample: Lung Cancer Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCC4 chr13 95019835 95301475 - ABLIM1 chr10 114431113 114768061 - ADGRV1 chr5 90529344 91164437 + AK4 chr1 65147549 65232145 + miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-214-3p chr1 172138816 172138837 - hsa-miR-185-5p chr22 20033153 20033174 + hsa-miR-302a-3p chr4 112648186 112648208 - hsa-miR-34c-5p chr11 111513451 111513473 + hsa-miR-302b-3p chr4 112648489 112648511 - hsa-miR-302c-3p chr4 112648366 112648388 - hsa-miR-302d-3p chr4 112648006 112648028 - hsa-miR-373-3p chr19 53788748 53788770 + hsa-miR-485-5p chr14 101055427 101055448 + hsa-miR-520e-3p chr19 53675764 53675784 + hsa-miR-520a-3p chr19 53690933 53690954 + hsa-miR-519b-3p chr19 53695263 53695284 + hsa-miR-520b-3p chr19 53701267 53701287 + hsa-miR-520c-3p chr19 53707506 53707527 + hsa-miR-520d-3p chr19 53720149 53720170 + hsa-miR-519a-3p chr19 53762397 53762418 + hsa-miR-873-5p chr9 28888925 28888945 - hsa-miR-1270 chr19 20399320 20399342 - hsa-miR-302e chr11 7234771 7234787 + hsa-miR-1321 chrX 85835832 85835849 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC245014.3 chr1 145281116 145281462 + Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22689099 Title: Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Author: Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW. Journal: Cell Mol Life Sci. 2012 Oct;69(19):3341-3350. Description: This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.