Entry Detail


General Information

Database ID:exR0504867
RNA Name:PLXNA1
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):126988594End Site(bp):127037392
External Links:ENSG00000114554



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
AATF
chr17
36948954
37056871
+
ABCA2
chr9
137007234
137028922
-
ABHD4
chr14
22598237
22613215
+
ACAD10
chr12
111686056
111757107
+
ADAM11
chr17
44758988
44781846
+
ADAM9
chr8
38996869
39105261
+
ADD1
chr4
2843857
2930076
+
AGBL5
chr2
27042364
27070622
+
AGO2
chr8
140520156
140635633
-
AL139011.2
chr1
160216800
160285130
-
AL162417.1
chr9
133098121
133163914
-
AL513165.2
chr9
37512547
37592469
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-96-5p
chr7
129774739
129774761
-
hsa-miR-7-5p
chr19
4770700
4770723
+
hsa-miR-182-5p
chr7
129770447
129770470
-
hsa-miR-205-5p
chr1
209432166
209432187
+
hsa-miR-185-5p
chr22
20033153
20033174
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC002470.2
chr22
20979462
20998121
+
AC012531.1
chr12
54019910
54022589
+
AC016586.1
chr19
4061615
4062749
-
AC022007.1
chr3
10004048
10011209
-
AC026740.1
chr5
675826
676616
+
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.