Entry Detail


General Information

Database ID:exR0506252
RNA Name:RPL8
RNA Type:mRNA
Chromosome:chr8
Starnd:-
Coordinate:
Start Site(bp):144789765End Site(bp):144792587
External Links:ENSG00000161016



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AHCY
chr20
34280268
34311802
-
ALDOA
chr16
30064164
30070457
+
AC124312.1
chr15
24955034
25000276
+
ACTB
chr7
5527148
5563784
-
AC105052.3
chr7
102637049
102671641
-
ALDH6A1
chr14
74056847
74084492
-
ADCK1
chr14
77800109
77935014
+
AC004922.1
chr7
99325879
99394653
+
ACTN1
chr14
68874143
68979440
-
AKIRIN1
chr1
38991276
39006059
+
AC092073.1
chr19
34396315
34409364
+
ADARB2
chr10
1177313
1737525
-
AIMP2
chr7
6009255
6023834
+
ACTN4
chr19
38647649
38731589
+
AC008982.1
chr19
38817471
38840178
-
AHSA1
chr14
77457870
77469472
+
ABHD12
chr20
25294742
25390835
-
AC027796.3
chr17
3585149
3636249
-
ACTG1
chr17
81509971
81523847
-
ACACA
chr17
37084992
37406836
-
ACTR5
chr20
38748460
38772520
+
ACTR2
chr2
65227753
65271253
+
AKAP8L
chr19
15380050
15419141
-
ADNP
chr20
50888916
50931437
-
AC011448.1
chr19
19516227
19536076
+
AL022238.4
chr22
40346529
40410054
+
AC018523.2
chr11
14493783
14520344
-
AGA
chr4
177430774
177442437
-
AC020909.1
chr19
50415799
50428409
+
ABHD17A
chr19
1876810
1885547
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4751
chr19
49933073
49933096
+
hsa-miR-6850-5p
chr8
144791970
144791991
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC005899.4
chr17
32328441
32329395
+
AC007952.4
chr17
19112000
19112636
-
AC016876.2
chr17
7581964
7584086
-
AC021242.3
chr8
9555144
9556520
-
AC026362.1
chr12
122975320
122982907
+
AC026461.1
chr16
56682470
56687807
+
AC060780.1
chr17
43148368
43171037
-
AC067930.1
chr8
143579636
143580670
+
AC092329.1
chr19
23257255
23274232
-
AC092329.4
chr19
23259906
23274251
-
AC099778.1
chr3
47379089
47380999
-
AC105105.1
chr18
58535415
58538552
+
AC105285.1
chr4
173094868
173169652
-
AC132217.1
chr11
2129121
2129964
-
AD000090.1
chr19
35557956
35581954
+
AL021707.1
chr22
38739003
38749041
+
AL022311.1
chr22
37876148
37895563
+
AL132780.1
chr14
22929607
22956374
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.