Entry Detail



General Information

Database ID:exR0506611
RNA Name:SEC16A
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):136440096End Site(bp):136483759
External Links:ENSG00000148396



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010422.3
chr19
12643831
12648397
-
AKIRIN1
chr1
38991276
39006059
+
AKT2
chr19
40230317
40285536
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-93-5p
chr7
100093815
100093837
-
hsa-miR-106a-5p
chrX
134170244
134170266
-
hsa-miR-302a-3p
chr4
112648186
112648208
-
hsa-miR-302b-3p
chr4
112648489
112648511
-
hsa-miR-302c-3p
chr4
112648366
112648388
-
hsa-miR-302d-3p
chr4
112648006
112648028
-
hsa-miR-373-3p
chr19
53788748
53788770
+
hsa-miR-520e-3p
chr19
53675764
53675784
+
hsa-miR-519c-3p
chr19
53686522
53686543
+
hsa-miR-520a-3p
chr19
53690933
53690954
+
hsa-miR-519b-3p
chr19
53695263
53695284
+
hsa-miR-520b-3p
chr19
53701267
53701287
+
hsa-miR-520c-3p
chr19
53707506
53707527
+
hsa-miR-520d-3p
chr19
53720149
53720170
+
hsa-miR-519a-3p
chr19
53762397
53762418
+
hsa-miR-302e
chr11
7234771
7234787
+
hsa-let-7c-5p
chr21
16539838
16539859
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC012313.3
chr19
58346854
58362751
-
AC020916.1
chr19
13823880
13842928
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.