exRNAdisease

Entry Detail

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General Information

Database ID: exR0507258 RNA Name: SLC6A6 RNA Type: mRNA Chromosome: chr3 Starnd: + Coordinate: Start Site(bp): 14402576 End Site(bp): 14489349 External Links: ENSG00000131389

Disease Information

Disease Name: Lung Cancer Disease Category: Cancers MeSH ID: D008175 Type: Neoplasms/Respiratory Tract Neoplasms Alias: Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung

Expression Detail

GEO ID: GSE32175 Description: Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer Experimental Design: Cancer vs Control Case Disease Type: Lung Cancer Case Disease SubType: NA Case Sample: Lung Cancer Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand AC005258.1 chr19 2269525 2341172 + ACOT7 chr1 6264269 6394391 - AEBP2 chr12 19404045 19720801 + AEN chr15 88621337 88632281 + AHCY chr20 34280268 34311802 - AKT1S1 chr19 49869033 49878459 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-miR-199a-5p chr1 172144592 172144614 - hsa-miR-34a-5p chr1 9151735 9151756 - hsa-miR-140-5p chr16 69933103 69933124 + hsa-miR-149-5p chr2 240456015 240456037 + hsa-miR-491-5p chr9 20716120 20716141 + hsa-miR-625-5p chr14 65471116 65471136 + hsa-miR-541-3p chr14 101064548 101064569 + hsa-miR-210-3p chr11 568112 568133 - circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC067930.1 chr8 143579636 143580670 + AC091564.7 chr11 6610883 6616594 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22689099 Title: Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Author: Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW. Journal: Cell Mol Life Sci. 2012 Oct;69(19):3341-3350. Description: This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.