exRNAdisease

Entry Detail

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General Information

Database ID: exR0507888 RNA Name: STK4 RNA Type: mRNA Chromosome: chr20 Starnd: + Coordinate: Start Site(bp): 44966479 End Site(bp): 45080021 External Links: ENSG00000101109

Disease Information

Disease Name: Lung Cancer Disease Category: Cancers MeSH ID: D008175 Type: Neoplasms/Respiratory Tract Neoplasms Alias: Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung

Expression Detail

GEO ID: GSE32175 Description: Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer Experimental Design: Cancer vs Control Case Disease Type: Lung Cancer Case Disease SubType: NA Case Sample: Lung Cancer Control Sample: Healthy Number of Case: 10 Number of Control: 10 Number of Samples: 20

Regulatory Relationship

mRNA targets: Gene Symbol Chromosome Start Site(bp) End Site(bp) Strand ABCF2 chr7 151207837 151227166 - AC245033.1 chr15 82536788 82573194 - AGPAT1 chr6 32168212 32178096 - AGTRAP chr1 11736084 11754802 + AKR1B1 chr7 134442356 134459284 - AKT3 chr1 243488233 243851079 - ALDH9A1 chr1 165662216 165698863 - miRNA targets: miRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand hsa-let-7a-5p chr9 94175962 94175983 + hsa-miR-24-3p chr9 95086064 95086085 + hsa-miR-122-5p chr18 58451088 58451109 + hsa-miR-130a-3p chr11 57641252 57641273 + hsa-miR-135a-5p chr12 97563834 97563856 + hsa-miR-138-5p chr16 56858527 56858549 + hsa-miR-130b-3p chr22 21653354 21653375 + hsa-miR-362-5p chrX 50008968 50008991 + hsa-miR-135b-5p chr1 205448361 205448383 - hsa-miR-1224-5p chr3 184241405 184241423 + hsa-miR-1276 chr15 85770548 85770567 - hsa-let-7c-5p chr21 16539838 16539859 + circRNA targets: NA lncRNA targets: lncRNA Symbol Chromosome Start Site(bp) End Site(bp) Strand AC016876.2 chr17 7581964 7584086 - AC087190.3 chr16 9104848 9113181 + AC245033.4 chr15 82533175 82540008 - Display:

Experiment Detail

GEO ID: NA Sample Source: NA Source Fraction: NA Platform: NA Method: NA Num of detected RNA Type: NA Num of detected RNAs of this Type: NA Sample treatment protocol: NA RNA Extract protocol: NA RNA library preparation protocol: NA

Reference

PMID: 22689099 Title: Development of transcriptomic biomarker signature in human saliva to detect lung cancer. Author: Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW. Journal: Cell Mol Life Sci. 2012 Oct;69(19):3341-3350. Description: This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.