Entry Detail


General Information

Database ID:exR0508566
RNA Name:TMBIM6
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):49707725End Site(bp):49764934
External Links:ENSG00000139644



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AKAP12
chr6
151239967
151358559
+
AGA
chr4
177430774
177442437
-
ACTB
chr7
5527148
5563784
-
AATF
chr17
36948954
37056871
+
ACBD5
chr10
27195214
27242130
-
ADAMTS1
chr21
26835755
26845409
-
AL353588.1
chr6
44273194
44378957
+
AC092647.5
chr7
55887277
55955239
+
AC026464.4
chr16
69299682
69322700
+
AGO2
chr8
140520156
140635633
-
ABCG2
chr4
88090150
88231628
-
AFF1
chr4
86935002
87141054
+
AC004997.1
chr22
30285238
30299482
-
AL139353.1
chr14
31334312
31457441
-
AC048338.1
chr12
122207779
122266423
-
AIF1L
chr9
131096476
131123152
+
AC078927.1
chr12
66123917
66169985
-
ACSF2
chr17
50426158
50474845
+
ADAM22
chr7
87934143
88202889
+
ABHD8
chr19
17292131
17310236
-
ALDOA
chr16
30064164
30070457
+
ACTG1
chr17
81509971
81523847
-
AHCY
chr20
34280268
34311802
-
ACO2
chr22
41469117
41528989
+
AC010422.3
chr19
12643831
12648397
-
AASDHPPT
chr11
106075501
106098699
+
ACTL6A
chr3
179562886
179588407
+
AL162417.1
chr9
133098121
133163914
-
AHNAK
chr11
62433542
62556235
-
ADRM1
chr20
62302093
62308862
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-423-5p
chr17
30117095
30117117
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC009446.1
chr8
71675300
71702786
+
AC012360.3
chr2
105334027
105337475
-
AC018521.1
chr17
47945424
47981736
+
AC020978.7
chr16
68224713
68227734
+
AC022140.1
chr5
25404733
25445925
-
AC023509.1
chr12
53441741
53467528
+
AD000090.1
chr19
35557956
35581954
+
AF129075.2
chr21
29058073
29060095
-
AL021707.3
chr22
38734730
38738990
+
AL049543.1
chr6
28587378
28591747
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.