Entry Detail


General Information

Database ID:exR0508889
RNA Name:TNPO2
RNA Type:mRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):12699194End Site(bp):12724011
External Links:ENSG00000105576



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMP
chr2
218264123
218270257
-
ABCE1
chr4
145098288
145129524
+
ABL2
chr1
179099330
179229684
-
AC007040.2
chr2
70939318
70995336
-
AC010422.3
chr19
12643831
12648397
-
AC011462.1
chr19
41350853
41425001
+
AC011530.1
chr19
45779437
45785973
-
AC091167.2
chr15
90249556
90272208
+
AC092647.5
chr7
55887277
55955239
+
ACACA
chr17
37084992
37406836
-
ACADVL
chr17
7217125
7225266
+
ACTB
chr7
5527148
5563784
-
ADAM11
chr17
44758988
44781846
+
ADAM8
chr10
133262420
133276868
-
ADARB1
chr21
45073853
45226560
+
ADCK2
chr7
140672945
140696261
+
ADGRE5
chr19
14380501
14408725
+
ADGRG2
chrX
18989307
19122637
-
AGAP1
chr2
235494043
236131800
+
AGAP3
chr7
151085831
151144436
+
AGPAT5
chr8
6708642
6761503
+
AGRN
chr1
1020120
1056118
+
AL136295.4
chr14
24180395
24190416
-
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4787-5p
chr3
50675093
50675114
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006538.1
chr19
2727743
2729327
-
AC011753.2
chr2
109594693
109605698
-
AC084125.2
chr8
144495458
144505444
-
AC109460.3
chr16
28974804
28990775
+
AD000090.1
chr19
35557956
35581954
+
AGAP11
chr10
86970741
87010126
+
AL049796.1
chr1
93847174
93848939
+
AL117379.1
chr20
62928621
62929297
-
AL136982.1
chr10
86992406
87010203
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.