Entry Detail


General Information

Database ID:exR0508916
RNA Name:TOP2A
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):40388525End Site(bp):40417896
External Links:ENSG00000131747



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASS
chr7
122073549
122144255
-
AC004832.3
chr22
30409255
30428990
+
AC010422.3
chr19
12643831
12648397
-
AC048338.1
chr12
122207779
122266423
-
AC091167.2
chr15
90249556
90272208
+
AC138811.2
chr16
18788063
18801519
-
ACACA
chr17
37084992
37406836
-
ACO1
chr9
32384603
32454769
+
ACP1
chr2
264140
278283
+
ACTG1
chr17
81509971
81523847
-
ADAMTS2
chr5
179110853
179345461
-
AGRN
chr1
1020120
1056118
+
AHCY
chr20
34280268
34311802
-
AICDA
chr12
8602170
8612867
-
AKAP1
chr17
57085092
57121346
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302a-3p
chr4
112648186
112648208
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC025287.1
chr16
75541399
75608445
-
AC067930.1
chr8
143579636
143580670
+
AC139149.1
chr17
81514047
81527776
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.