Entry Detail


General Information

Database ID:exR0508963
RNA Name:TPM4
RNA Type:mRNA
Chromosome:chr19
Starnd:+
Coordinate:
Start Site(bp):16067021End Site(bp):16103002
External Links:ENSG00000167460



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AAMDC
chr11
77821109
77918432
+
AAMP
chr2
218264123
218270257
-
AARSD1
chr17
42950526
42964498
-
ABL1
chr9
130713016
130887675
+
AC004922.1
chr7
99325879
99394653
+
AC007192.1
chr19
18153158
18178117
+
AC048338.1
chr12
122207779
122266423
-
AC138696.1
chr8
143247110
143276403
+
AC245033.1
chr15
82536788
82573194
-
ACLY
chr17
41866917
41930542
-
ACTB
chr7
5527148
5563784
-
ACTG1
chr17
81509971
81523847
-
ADCY5
chr3
123282296
123449758
-
ADCY6
chr12
48766194
48789037
-
ADIPOR2
chr12
1688574
1788674
+
ADPGK
chr15
72751369
72785846
-
ADRM1
chr20
62302093
62308862
+
AGAP3
chr7
151085831
151144436
+
AHCY
chr20
34280268
34311802
-
AKT2
chr19
40230317
40285536
-
AL136454.1
chr1
192716132
192716653
+
AL365205.1
chr6
41780349
41790141
+
ALDOA
chr16
30064164
30070457
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-139-5p
chr11
72615102
72615124
-
hsa-miR-185-5p
chr22
20033153
20033174
+
hsa-miR-1270
chr19
20399320
20399342
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC008969.1
chr19
58002061
58011232
+
AC016876.2
chr17
7581964
7584086
-
AC026362.1
chr12
122975320
122982907
+
AC026464.2
chr16
69463844
69466264
+
AC079807.1
chr2
47905678
47907810
+
AC099343.3
chr4
184471924
184472609
-
AC132217.1
chr11
2129121
2129964
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.