Entry Detail


General Information

Database ID:exR0509586
RNA Name:USP22
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):20999596End Site(bp):21043760
External Links:ENSG00000124422



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AARS2
chr6
44298731
44313347
-
ABCB1
chr7
87503017
87713323
-
AC005726.1
chr17
28455752
28614185
-
AC008581.2
chr5
77030902
77152155
+
AC008695.1
chr5
131425891
131796983
-
AC010422.3
chr19
12643831
12648397
-
AC138811.2
chr16
18788063
18801519
-
ACBD3
chr1
226144679
226186741
-
ACIN1
chr14
23058564
23095614
-
ACLY
chr17
41866917
41930542
-
ADH5
chr4
99070978
99088801
-
ADSL
chr22
40346500
40390463
+
AGGF1
chr5
77029251
77065234
+
AHCY
chr20
34280268
34311802
-
AKR1B1
chr7
134442356
134459284
-
AL022238.4
chr22
40346529
40410054
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-148b-3p
chr12
54337278
54337299
+
hsa-miR-485-5p
chr14
101055427
101055448
+
hsa-miR-650
chr22
22822791
22822811
+
hsa-miR-371a-5p
chr19
53787680
53787699
+
hsa-miR-616-3p
chr12
57519183
57519204
-
hsa-miR-665
chr14
100875075
100875094
+
hsa-miR-1321
chrX
85835832
85835849
+
hsa-miR-4508
chr15
23562107
23562123
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC006064.5
chr12
6510275
6510522
+
AC007952.4
chr17
19112000
19112636
-
AC011445.1
chr19
39314651
39320858
-
AC016876.2
chr17
7581964
7584086
-
AC026362.1
chr12
122975320
122982907
+
AC067852.1
chr17
42536510
42562062
+
AC067930.1
chr8
143579636
143580670
+
AC087190.3
chr16
9104848
9113181
+
AC111170.2
chr17
77469162
77472770
-
AC133644.3
chr2
87455476
87767359
+
AD000090.1
chr19
35557956
35581954
+
AL022311.1
chr22
37876148
37895563
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.