Entry Detail


General Information

Database ID:exR0509954
RNA Name:XRCC6
RNA Type:mRNA
Chromosome:chr22
Starnd:+
Coordinate:
Start Site(bp):41621119End Site(bp):41664048
External Links:ENSG00000196419



Disease Information

Disease Name:Lung Cancer
Disease Category:Cancers
MeSH ID:D008175
Type:Neoplasms/Respiratory Tract Neoplasms
Alias:Lung Neoplasms//Pulmonary Neoplasms//Neoplasms, Lung//Lung Neoplasm//Neoplasm, Lung//Neoplasms, Pulmonary//Neoplasm, Pulmonary//Pulmonary Neoplasm//Lung Cancer//Cancer, Lung//Cancers, Lung//Lung Cancers//Pulmonary Cancer//Cancer, Pulmonary//Cancers, Pulmonary//Pulmonary Cancers//Cancer of the Lung//Cancer of Lung



Expression Detail

GEO ID:GSE32175
Description:Development of Transcriptomic Biomarker Signature in Human Saliva to Detect Lung Cancer
Experimental Design:Cancer vs Control
Case Disease Type:Lung Cancer
Case Disease SubType:NA
Case Sample:Lung Cancer
Control Sample:Healthy
Number of Case:10
Number of Control:10
Number of Samples:20





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AASDHPPT
chr11
106075501
106098699
+
ABR
chr17
1003518
1229738
-
ABRAXAS1
chr4
83459517
83523348
-
AC005020.2
chr7
99558695
99607810
+
AC010132.3
chr7
42909273
42932174
-
AC010422.3
chr19
12643831
12648397
-
AC068946.1
chr2
219075329
219170827
-
AC099811.2
chr17
42119674
42154916
-
AC120057.2
chr17
7240427
7244635
-
ACADVL
chr17
7217125
7225266
+
ACOT8
chr20
45841721
45857405
-
ACTN1
chr14
68874143
68979440
-
ACTR1A
chr10
102461881
102502712
-
ADAM10
chr15
58588809
58749791
-
ADAM15
chr1
155050566
155062775
+
ADCY3
chr2
24819169
24919839
-
AKR1B1
chr7
134442356
134459284
-
AL358113.1
chr9
69035747
69255187
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-17-5p
chr13
91350618
91350640
+
hsa-miR-18a-5p
chr13
91350756
91350778
+
hsa-miR-205-5p
chr1
209432166
209432187
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC079781.5
chr7
97851688
97972985
-
AC093157.1
chr1
101025844
101090513
+
AC144548.1
chr12
110387463
110445548
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22689099
Title:Development of transcriptomic biomarker signature in human saliva to detect lung cancer.
Author:Zhang L(#), Xiao H(#), Zhou H, Santiago S, Lee JM, Garon EB,Yang J, Brinkmann O, Yan X, Akin D, Chia D, Elashoff D, ParkNH, Wong DTW.
Journal:Cell Mol Life Sci. 2012 Oct;69(19):3341-3350.
Description:This report provides theproof of concept of salivary biomarkers for the non-invasive detection of thesystematic disease.