Entry Detail


General Information

Database ID:exR0510730
RNA Name:AAAS
RNA Type:mRNA
Chromosome:chr12
Starnd:-
Coordinate:
Start Site(bp):53307456End Site(bp):53324864
External Links:ENSG00000094914



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
MSI1
chr12
120341330
120369164
-
RPL11
chr1
23691742
23696835
+
RPLP2
chr11
809965
812880
+
MIF
chr22
23894383
23895227
+
MRPS10
chr6
42206807
42217861
-
RCSD1
chr1
167630093
167708696
+
LRCH4
chr7
100574011
100586129
-
LRP2
chr2
169127109
169362534
-
MEX3C
chr18
51174550
51218304
-
MTRNR2L12
chr3
96617188
96618236
-
MTA1
chr14
105419820
105470729
+
B2M
chr15
44711487
44718877
+
CDC25B
chr20
3786772
3806121
+
SFPQ
chr1
35176378
35193145
-
ZNF207
chr17
32350117
32381886
+
VPS41
chr7
38722974
38932394
-
RPL13
chr16
89560657
89566828
+
METTL16
chr17
2405562
2511891
-
MAPK14
chr6
36027677
36111236
+
CD99
chrX
2691187
2741309
+
YBX3
chr12
10699089
10723323
-
AP000350.4
chr22
23862188
23895223
+
PKM
chr15
72199029
72231822
-
FRAS1
chr4
78057323
78544269
+
LRIG1
chr3
66378797
66501263
-
RACK1
chr5
181236897
181248096
-
ALDOA
chr16
30064164
30070457
+
MYL6
chr12
56158161
56163496
+
NBR1
chr17
43170481
43211689
+
LAMA5
chr20
62307955
62367312
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC069281.2
chr7
100572232
100578700
-
PCAT6
chr1
202810954
202812156
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.