Entry Detail


General Information

Database ID:exR0510736
RNA Name:AADAT
RNA Type:mRNA
Chromosome:chr4
Starnd:-
Coordinate:
Start Site(bp):170060222End Site(bp):170091699
External Links:ENSG00000109576



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ARL4C
chr2
234493041
234497081
-
B3GALNT2
chr1
235447190
235504452
-
CPD
chr17
30378927
30469989
+
EP400
chr12
131949942
132080460
+
FOXF2
chr6
1389576
1395603
+
FXR1
chr3
180868141
180982753
+
GNAS
chr20
58839718
58911192
+
HOXA1
chr7
27093313
27095996
-
LRP8
chr1
53242364
53328469
-
MACF1
chr1
39081316
39487177
+
NCSTN
chr1
160343316
160358952
+
NDUFB3
chr2
201071433
201085750
+
PGS1
chr17
78378649
78425114
+
PSMD3
chr17
39980807
39997959
+
RABL6
chr9
136807943
136841187
+
ZNF43
chr19
21804949
21852125
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-15a-5p
chr13
50049167
50049188
-
hsa-miR-15b-5p
chr3
160404607
160404628
+
hsa-miR-424-5p
chrX
134546680
134546701
-
hsa-miR-497-5p
chr17
7017979
7017999
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL355987.4
chr9
136799223
136810042
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.