Entry Detail


General Information

Database ID:exR0510742
RNA Name:AARSD1
RNA Type:mRNA
Chromosome:chr17
Starnd:-
Coordinate:
Start Site(bp):42950526End Site(bp):42964498
External Links:ENSG00000266967



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
PTMS
chr12
6765516
6770952
+
KBTBD7
chr13
41189834
41194569
-
PPDPF
chr20
63520765
63522206
+
PPP1CC
chr12
110719680
110742939
-
BLOC1S5-TXNDC5
chr6
7881522
8064364
-
ZNF777
chr7
149431363
149461062
-
CALM3
chr19
46601074
46610782
+
HIGD2A
chr5
176388751
176389761
+
RPL35A
chr3
197950190
197956610
+
HNRNPF
chr10
43385617
43409166
-
CCNT2
chr2
134918235
134959342
+
ERI2
chr16
20780193
20900349
-
RPUSD3
chr3
9837849
9844602
-
TPT1
chr13
45333471
45341370
-
RNPS1
chr16
2253116
2268397
-
CALR
chr19
12938578
12944489
+
PTGES3L-AARSD1
chr17
42950526
42980528
-
RNF213
chr17
80260866
80398786
+
SASH3
chrX
129779949
129795201
+
EDARADD
chr1
236348257
236502915
+
CST3
chr20
23626706
23638473
-
SKI
chr1
2228319
2310213
+
MRPL13
chr8
120380761
120445402
-
TMEM258
chr11
61768501
61792802
-
ASB8
chr12
48147789
48181213
-
RPL27
chr17
42998273
43002959
+
GSPT2
chrX
51743442
51746232
+
TXNDC5
chr6
7881517
7910788
-
DYNLL1
chr12
120469850
120498493
+
TRMU
chr22
46330875
46357340
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
Z95114.1
chr22
36071000
36085573
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.