Entry Detail


General Information

Database ID:exR0510745
RNA Name:AASS
RNA Type:mRNA
Chromosome:chr7
Starnd:-
Coordinate:
Start Site(bp):122073549End Site(bp):122144255
External Links:ENSG00000008311



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
IRF3
chr19
49659569
49665875
-
CDK2
chr12
55966781
55972789
+
FUBP1
chr1
77944055
77979110
-
CDC34
chr19
531760
542092
+
AC010422.3
chr19
12643831
12648397
-
NDUFA4
chr7
10931943
10940153
-
ACTG1
chr17
81509971
81523847
-
C16orf70
chr16
67109941
67148544
+
AC015813.2
chr17
57989038
58007246
-
MATR3
chr5
139273752
139331671
+
QSOX1
chr1
180154869
180204030
+
FAR1
chr11
13668668
13732346
+
LMNB2
chr19
2427638
2456959
-
PKM
chr15
72199029
72231822
-
RPL18A
chr19
17859910
17864153
+
HDLBP
chr2
241227264
241317061
-
WDR3
chr1
117929720
117966543
+
ATP8B2
chr1
154325553
154351304
+
SLC25A5
chrX
119468422
119471396
+
SRSF5
chr14
69726900
69772005
+
ACTN1
chr14
68874143
68979440
-
ATP6V1G2-DDX39B
chr6
31530219
31546608
-
ADAMTS8
chr11
130404923
130428609
-
NASP
chr1
45583846
45618904
+
STX6
chr1
180972712
181023121
-
SLC25A28
chr10
99610522
99620609
-
RICTOR
chr5
38937920
39074399
-
LARP1
chr5
154712843
154817605
+
EIF3L
chr22
37848868
37889407
+
CMTM6
chr3
32481312
32502852
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC106864.1
chr4
112693047
112706810
-
AC138904.1
chr16
28284885
28292064
-
AL022311.1
chr22
37876148
37895563
+
AC068831.7
chr15
91022766
91023200
+
GABPB1-AS1
chr15
50354959
50372202
+
NORAD
chr20
36045618
36051018
-
ZBED3-AS1
chr5
77086688
77166909
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.