Entry Detail


General Information

Database ID:exR0510746
RNA Name:AATF
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):36948954End Site(bp):37056871
External Links:ENSG00000275700



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
SSR1
chr6
7268306
7347446
-
RPS19
chr19
41860255
41872925
+
THY1
chr11
119417378
119424985
-
EIF3B
chr7
2354086
2380745
+
CD74
chr5
150400041
150412929
-
CASP2
chr7
143288215
143307696
+
BDH1
chr3
197509783
197573323
-
RNF113A
chrX
119870475
119871733
-
RTCA
chr1
100266207
100292769
+
AP002990.1
chr11
62559603
62591531
-
CKB
chr14
103519667
103522833
-
CLDN23
chr8
8701937
8704096
+
RPL8
chr8
144789765
144792587
-
VLDLR
chr9
2621787
2660056
+
ACTB
chr7
5527148
5563784
-
MT-CO3
chrMT
9207
9990
+
RPS6
chr9
19375715
19380236
-
NIPA2
chr15
22838641
22868384
+
UBA52
chr19
18571730
18577550
+
DYNC1H1
chr14
101964573
102056443
+
UBALD2
chr17
76265348
76271298
+
LSM1
chr8
38163335
38176730
-
CIC
chr19
42268537
42295797
+
PAQR3
chr4
78887127
78939438
-
CCNA2
chr4
121816444
121823933
-
TMEM258
chr11
61768501
61792802
-
ACTR1B
chr2
97655939
97664044
-
CIT
chr12
119685791
119877320
-
FAN1
chr15
30890559
30943108
+
SRGN
chr10
69088103
69104805
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-4492
chr11
118910765
118910781
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL355987.4
chr9
136799223
136810042
+
NAALADL2-AS2
chr3
175234861
175271096
-
SNHG1
chr11
62851984
62855953
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.