Entry Detail


General Information

Database ID:exR0510749
RNA Name:ABCA1
RNA Type:mRNA
Chromosome:chr9
Starnd:-
Coordinate:
Start Site(bp):104781006End Site(bp):104928155
External Links:ENSG00000165029



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
COX5B
chr2
97646062
97648383
+
EIF3L
chr22
37848868
37889407
+
EWSR1
chr22
29268009
29300525
+
FEN1
chr11
61792911
61797238
+
GANAB
chr11
62624826
62646726
-
GAPDH
chr12
6534512
6538374
+
HADH
chr4
107989714
108035175
+
IGF2
chr11
2129112
2141238
-
IGF2BP3
chr7
23310209
23470491
-
KDM3B
chr5
138352685
138437028
+
LSMEM1
chr7
112480853
112491062
+
LUC7L3
chr17
50719565
50756219
+
MPI
chr15
74890005
74902219
+
NISCH
chr3
52455118
52493068
+
PIANP
chr12
6693792
6700800
-
PPRC1
chr10
102132994
102150333
+
RPL13A
chr19
49487554
49492308
+
RPL14
chr3
40457292
40468587
+
RPL19
chr17
39200283
39204732
+
RPS23
chr5
82273320
82278396
-
SEC11A
chr15
84669538
84716460
-
SHROOM3
chr4
76435229
76783253
+
SND1
chr7
127652194
128092609
+
UBE2R2
chr9
33817160
33920399
+
ZNF217
chr20
53567065
53609907
-
ZNF568
chr19
36916329
36998700
+
ZNF696
chr8
143289676
143299952
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-1294
chr5
154347153
154347174
+
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.