Entry Detail


General Information

Database ID:exR0510781
RNA Name:ABCF1
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):30571393End Site(bp):30597179
External Links:ENSG00000204574



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
HLA-DRB1
chr6
32578769
32589848
-
ZNF501
chr3
44729596
44737083
+
TMEM250
chr9
136114581
136118875
-
MT-CO1
chrMT
5904
7445
+
GLUL
chr1
182381704
182392206
-
CIC
chr19
42268537
42295797
+
MTRNR2L8
chr11
10507894
10509186
-
MYLIP
chr6
16129086
16148248
+
IFIT3
chr10
89327997
89340971
+
ZNF581
chr19
55635459
55645623
+
MAU2
chr19
19320829
19358754
+
CERS2
chr1
150960583
150975004
-
TNRC6A
chr16
24610209
24827632
+
PDP2
chr16
66878589
66895754
+
BSG
chr19
571277
583493
+
EEF1G
chr11
62559596
62574086
-
PTBP1
chr19
797075
812327
+
AP1S2
chrX
15825806
15854931
-
FTL
chr19
48965309
48966879
+
IQGAP1
chr15
90388242
90502239
+
SURF4
chr9
133361450
133376166
-
SELENON
chr1
25800176
25818221
+
RPS6
chr9
19375715
19380236
-
PDCD6IP
chr3
33798571
33869707
+
GPC6
chr13
93226807
94408020
+
VPS26A
chr10
69123512
69174412
+
CYFIP2
chr5
157266079
157395595
+
MFSD5
chr12
53251251
53254405
+
AC005832.4
chr12
4604944
4662643
+
BZW2
chr7
16646131
16706523
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-302c-3p
chr4
112648366
112648388
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC000068.1
chr22
19447893
19450105
+
AC010642.2
chr19
58309727
58327248
-
DANCR
chr4
52712404
52720351
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.