Entry Detail


General Information

Database ID:exR0510798
RNA Name:ABHD2
RNA Type:mRNA
Chromosome:chr15
Starnd:+
Coordinate:
Start Site(bp):89087459End Site(bp):89202355
External Links:ENSG00000140526



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
NUP210
chr3
13316235
13420322
-
RPS21
chr20
62387103
62388520
+
RPS6KB2
chr11
67428460
67435401
+
MT-ND5
chrMT
12337
14148
+
PPIF
chr10
79347469
79355334
+
BRD2
chr6
32968594
32981505
+
MMD
chr17
55392622
55421924
-
AP3S2
chr15
89830599
89894638
-
EEF1A1
chr6
73515750
73523797
-
PABPC3
chr13
25095868
25099254
+
MKRN1
chr7
140453033
140479536
-
AC024592.3
chr19
5866171
5903787
-
SHC2
chr19
416583
460996
-
DMWD
chr19
45782947
45792845
-
RPUSD3
chr3
9837849
9844602
-
PTGIS
chr20
49503874
49568137
-
METTL2A
chr17
62423867
62450822
+
EMC3
chr3
9962537
10011116
-
NDUFA11
chr19
5891276
5904006
-
KMT2D
chr12
49018975
49059774
-
CMTM3
chr16
66603874
66613892
+
HLA-A
chr6
29941260
29945884
+
CWC27
chr5
64768930
65018750
+
CCDC174
chr3
14651746
14672659
+
ATP5F1A
chr18
46080248
46104334
-
RNF40
chr16
30761745
30776307
+
MACF1
chr1
39081316
39487177
+
HOXD4
chr2
176151550
176153226
+
TSSC4
chr11
2400488
2403878
+
SALL2
chr14
21521080
21537216
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-15a-5p
chr13
50049167
50049188
-
hsa-miR-103a-3p
chr5
168560904
168560926
-
hsa-miR-107
chr10
89592756
89592778
-
hsa-miR-214-3p
chr1
172138816
172138837
-
hsa-miR-15b-5p
chr3
160404607
160404628
+
hsa-miR-195-5p
chr17
7017667
7017687
-
hsa-miR-497-5p
chr17
7017979
7017999
-
hsa-miR-423-5p
chr17
30117095
30117117
+
hsa-miR-532-3p
chrX
50003204
50003225
+
hsa-miR-541-3p
chr14
101064548
101064569
+
hsa-miR-665
chr14
100875075
100875094
+
hsa-miR-873-5p
chr9
28888925
28888945
-
hsa-miR-1294
chr5
154347153
154347174
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC067930.1
chr8
143579636
143580670
+
AC104257.1
chr8
131308545
131317632
+
AC079949.1
chr12
127142029
127146532
-
MUC20-OT1
chr3
195658062
195739964
+
SNAI3-AS1
chr16
88663298
88687278
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.