Entry Detail


General Information

Database ID:exR0510800
RNA Name:ABHD4
RNA Type:mRNA
Chromosome:chr14
Starnd:+
Coordinate:
Start Site(bp):22598237End Site(bp):22613215
External Links:ENSG00000100439



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
FAM219A
chr9
34398184
34458570
-
RPL32
chr3
12834485
12841582
-
ZNF708
chr19
21291160
21329425
-
AP2A1
chr19
49766968
49807113
+
ARHGEF4
chr2
130836916
131047263
+
POLD4
chr11
67350772
67356972
-
PITPNC1
chr17
67377281
67697261
+
TUBA1A
chr12
49184795
49189080
-
TRIP6
chr7
100867387
100873454
+
AXIN1
chr16
287440
352723
-
HAT1
chr2
171922448
171983686
+
MYL12A
chr18
3247481
3256236
+
HNRNPA1
chr12
54280193
54287088
+
PSMB8
chr6
32840717
32844679
-
MT-CO1
chrMT
5904
7445
+
GAPDH
chr12
6534512
6538374
+
CNPPD1
chr2
219171897
219178106
-
DDX1
chr2
15591178
15631111
+
HNRNPK
chr9
83968083
83980616
-
OGT
chrX
71533104
71575892
+
PUM1
chr1
30931506
31065991
-
BTBD2
chr19
1985438
2034881
-
PSAP
chr10
71816298
71851325
-
EWSR1
chr22
29268009
29300525
+
EIF6
chr20
35278911
35284985
-
KDM5B
chr1
202724495
202808487
-
CBSL
chr21
6444869
6468040
-
AL121753.1
chr20
35267885
35280043
-
CCT8
chr21
29055805
29073797
-
TRPV3
chr17
3510502
3557995
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-31-5p
chr9
21512158
21512178
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AGAP1-IT1
chr2
235505751
235507566
+
GATA2-AS1
chr3
128489212
128502970
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.