Entry Detail


General Information

Database ID:exR0510801
RNA Name:ABHD5
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):43690108End Site(bp):43734371
External Links:ENSG00000011198



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
KIAA1143
chr3
44737661
44761619
-
RPLP1
chr15
69452814
69456205
+
LGALS3BP
chr17
78971238
78979947
-
ATF7IP
chr12
14365632
14502935
+
TOMM22
chr22
38681957
38685421
+
TIAF1
chr17
29073521
29078857
-
TMSB4X
chrX
12975110
12977227
+
NIPSNAP1
chr22
29554808
29581327
-
DCAF10
chr9
37800554
37867666
+
ZFAT
chr8
134477788
134713049
-
THOC5
chr22
29505879
29555216
-
CNN2
chr19
1026586
1039068
+
GALNT2
chr1
230057990
230282122
+
MYO18A
chr17
29071124
29180412
-
PLBD2
chr12
113358566
113391629
+
HS3ST3B1
chr17
14301081
14349404
+
TUBB4B
chr9
137241287
137243707
+
RPL18A
chr19
17859910
17864153
+
TUBB
chr6
30720352
30725426
+
AC010422.3
chr19
12643831
12648397
-
CBSL
chr21
6444869
6468040
-
ATP5MC3
chr2
175176258
175184607
-
CBS
chr21
43053191
43076943
-
ANO10
chr3
43354859
43691594
-
ZNF75D
chrX
135248920
135344109
-
SEH1L
chr18
12947133
12987536
+
DICER1
chr14
95086228
95158010
-
GDI1
chrX
154436913
154443467
+
PTMA
chr2
231706895
231713541
+
HSD17B4
chr5
119452473
119637199
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
U73166.1
chr3
50260303
50263358
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.