Entry Detail


General Information

Database ID:exR0510802
RNA Name:ABHD6
RNA Type:mRNA
Chromosome:chr3
Starnd:+
Coordinate:
Start Site(bp):58237532End Site(bp):58295693
External Links:ENSG00000163686



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010422.3
chr19
12643831
12648397
-
AMY2B
chr1
103553815
103579534
+
FSTL1
chr3
120392293
120450993
-
GSKIP
chr14
96363452
96387288
+
HLA-B
chr6
31269491
31357188
-
NDUFA10
chr2
239892450
240025345
-
NME2
chr17
51165435
51171747
+
PSMD14
chr2
161308425
161411717
+
RPL27A
chr11
8682788
8714759
+
SLC12A8
chr3
125082636
125212864
-
SLC25A29
chr14
100291116
100306547
-
SMU1
chr9
33041765
33076674
-
SRSF5
chr14
69726900
69772005
+
SSBP4
chr19
18418864
18434562
+
TERF2IP
chr16
75647773
75761872
+
TICRR
chr15
89575469
89631056
+
TMED7
chr5
115613210
115632992
-
TPI1
chr12
6867119
6870948
+
UBR7
chr14
93207241
93229215
+
VIM
chr10
17228241
17237593
+
WIPF1
chr2
174559572
174682916
-
ZFAND2B
chr2
219195237
219209651
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC016598.1
chr5
143489855
143531350
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.