Entry Detail


General Information

Database ID:exR0510803
RNA Name:ABHD8
RNA Type:mRNA
Chromosome:chr19
Starnd:-
Coordinate:
Start Site(bp):17292131End Site(bp):17310236
External Links:ENSG00000127220



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ITM2C
chr2
230864639
230879248
+
TUBA3C
chr13
19173772
19181824
-
CAP1
chr1
40040233
40072649
+
HOXB5
chr17
48591257
48593961
-
RPLP2
chr11
809965
812880
+
ARHGEF7
chr13
111114559
111305737
+
NAP1L1
chr12
76036585
76084958
-
DUSP2
chr2
96143169
96145440
-
CHST11
chr12
104455295
104762014
+
IGFBP2
chr2
216632828
216664436
+
GALNS
chr16
88813734
88856970
-
RPS19
chr19
41860255
41872925
+
PTMS
chr12
6765516
6770952
+
EMC10
chr19
50476400
50490870
+
EIF4G2
chr11
10797050
10808940
-
DDX17
chr22
38483438
38507660
-
LRRC14
chr8
144517992
144525172
+
PTK7
chr6
43076307
43161719
+
FSTL1
chr3
120392293
120450993
-
DNASE2
chr19
12875209
12881466
-
ANXA11
chr10
80150889
80205572
-
UCHL1
chr4
41256413
41268455
+
S100A10
chr1
151982915
151993859
-
CITED4
chr1
40861054
40862363
-
DBN1
chr5
177456608
177474401
-
PKM
chr15
72199029
72231822
-
MDK
chr11
46380756
46383837
+
GALNT17
chr7
71132144
71713600
+
ZFP91
chr11
58579063
58621550
+
RPS28
chr19
8321158
8323340
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC069281.2
chr7
100572232
100578700
-
AD000090.1
chr19
35557956
35581954
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.