Entry Detail


General Information

Database ID:exR0510804
RNA Name:ABI1
RNA Type:mRNA
Chromosome:chr10
Starnd:-
Coordinate:
Start Site(bp):26746593End Site(bp):26861087
External Links:ENSG00000136754



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
B2M
chr15
44711487
44718877
+
RPS27L
chr15
63125872
63158021
-
MTRNR2L1
chr17
22523111
22524663
+
PSMB1
chr6
170535120
170553307
-
COPG1
chr3
129249606
129277773
+
TTF1
chr9
132375548
132406851
-
TCEA1
chr8
53966552
54022456
-
AGK
chr7
141551278
141655244
+
WAC
chr10
28532493
28623112
+
ACLY
chr17
41866917
41930542
-
SUMO3
chr21
44805617
44818779
-
LARP1
chr5
154712843
154817605
+
IL10RB
chr21
33266367
33310187
+
RNF125
chr18
32018825
32073219
+
AFF1
chr4
86935002
87141054
+
PTMS
chr12
6765516
6770952
+
UBE3C
chr7
157138916
157269370
+
THOP1
chr19
2785503
2815807
+
SLC30A5
chr5
69093949
69131069
+
KIF23
chr15
69414246
69448427
+
PAN3
chr13
28138506
28295335
+
CCT4
chr2
61868085
61888671
-
BUB1
chr2
110637528
110678063
-
MTHFD2
chr2
74198610
74217565
+
ARID1A
chr1
26693236
26782104
+
TAF10
chr11
6606294
6612539
-
MYO19
chr17
36495633
36543435
-
SRRM2
chr16
2752626
2772538
+
SRPK1
chr6
35832966
35921342
-
RPLP1
chr15
69452814
69456205
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC091564.7
chr11
6610883
6616594
-
AL158066.1
chr13
52167709
52291557
-
AL355075.4
chr14
20343048
20343685
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.