Entry Detail


General Information

Database ID:exR0510805
RNA Name:ABI2
RNA Type:mRNA
Chromosome:chr2
Starnd:+
Coordinate:
Start Site(bp):203328239End Site(bp):203447728
External Links:ENSG00000138443



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
C15orf39
chr15
75195643
75212169
+
KLC1
chr14
103561896
103714249
+
PGAM1
chr10
97426191
97433444
+
ESPL1
chr12
53268299
53293638
+
COX5B
chr2
97646062
97648383
+
MYH9
chr22
36281277
36388067
-
YWHAQ
chr2
9583967
9630997
-
HLA-DQA1
chr6
32628179
32647062
+
MAN1B1
chr9
137086985
137109183
+
PUDP
chrX
6667865
7148190
-
PEX19
chr1
160276812
160286348
-
PKM
chr15
72199029
72231822
-
TRAF7
chr16
2155698
2178129
+
DICER1
chr14
95086228
95158010
-
LAMTOR4
chr7
100148907
100155944
+
ATN1
chr12
6924463
6942321
+
LMNB1
chr5
126776623
126837020
+
AL139300.1
chr14
103562962
103685924
+
SLC15A4
chr12
128793194
128823958
-
CCT2
chr12
69585426
69601570
+
NPLOC4
chr17
81556887
81648465
-
MT-CO3
chrMT
9207
9990
+
SLC9A3R1
chr17
74748628
74769353
+
API5
chr11
43311963
43344529
+
HSDL2
chr9
112380080
112472405
+
BOLA2-SMG1P6
chr16
29443230
29454651
-
TXNDC5
chr6
7881517
7910788
-
C9orf40
chr9
74946583
74952912
-
RPL22L1
chr3
170864875
170870208
-
HYOU1
chr11
119044188
119057227
-
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-218-5p
chr5
168768211
168768231
-
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC079354.2
chr2
202178660
202179391
-
ARHGAP27P1-BPTFP1-KPNA2P3
chr17
64749663
64781707
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.