Entry Detail


General Information

Database ID:exR0510806
RNA Name:ABI3
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):49210411End Site(bp):49223225
External Links:ENSG00000108798



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC010422.3
chr19
12643831
12648397
-
ANKRD46
chr8
100509752
100559784
-
CDC37
chr19
10391133
10420121
-
CFLAR
chr2
201116154
201176687
+
ETAA1
chr2
67397322
67412089
+
GRK2
chr11
67266473
67286556
+
HSPA8
chr11
123057489
123063230
-
LMNB2
chr19
2427638
2456959
-
MSN
chrX
65588377
65741931
+
MYL6B
chr12
56152256
56159647
+
PBK
chr8
27809624
27838082
-
PPP1R32
chr11
61481120
61490931
+
PPP4C
chr16
30075978
30085376
+
PTDSS2
chr11
448268
491399
+
RHOG
chr11
3826978
3840959
-
RPL8
chr8
144789765
144792587
-
RPS8
chr1
44775251
44778779
+
SKP1
chr5
134148935
134177038
-
TMEM216
chr11
61392360
61398863
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.