Entry Detail


General Information

Database ID:exR0510809
RNA Name:ABL2
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):179099330End Site(bp):179229684
External Links:ENSG00000143322



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
FBXL19
chr16
30923055
30948783
+
AC010422.3
chr19
12643831
12648397
-
SRPK2
chr7
105110704
105399308
-
KIAA0753
chr17
6578147
6640711
-
WDR74
chr11
62832342
62841809
-
RPL11
chr1
23691742
23696835
+
DNAH1
chr3
52316319
52400491
+
APBB3
chr5
140558268
140564781
-
HECTD4
chr12
112160188
112382439
-
RPS3
chr11
75399515
75422280
+
ARPP19
chr15
52547045
52569883
-
INPPL1
chr11
72223701
72239147
+
LRWD1
chr7
102464956
102473168
+
KPNA5
chr6
116681187
116741867
+
RPL12
chr9
127447674
127451406
-
KMT2D
chr12
49018975
49059774
-
UGDH
chr4
39498755
39528311
-
ZC4H2
chrX
64915802
65034713
-
PTMA
chr2
231706895
231713541
+
PDPN
chr1
13583465
13617957
+
CHCHD10
chr22
23765834
23768443
-
FUCA2
chr6
143494812
143511720
-
TEAD3
chr6
35473597
35497079
-
HNRNPM
chr19
8444767
8489114
+
ABL1
chr9
130713016
130887675
+
GLUL
chr1
182381704
182392206
-
UBR4
chr1
19074510
19210266
-
SSR2
chr1
156009048
156020951
-
RPL13A
chr19
49487554
49492308
+
IMP4
chr2
130342877
130347967
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-154-5p
chr14
101059769
101059790
+
hsa-miR-188-5p
chrX
50003517
50003537
+
hsa-miR-339-5p
chr7
1022990
1023012
-
hsa-miR-625-5p
chr14
65471116
65471136
+
hsa-miR-425-5p
chr3
49020199
49020221
-
hsa-miR-532-3p
chrX
50003204
50003225
+
hsa-miR-1224-5p
chr3
184241405
184241423
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
HIPK1-AS1
chr1
113924000
113929495
-
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.