Entry Detail


General Information

Database ID:exR0510810
RNA Name:ABLIM1
RNA Type:mRNA
Chromosome:chr10
Starnd:-
Coordinate:
Start Site(bp):114431113End Site(bp):114768061
External Links:ENSG00000099204



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
CDH1
chr16
68737292
68835541
+
SMIM14
chr4
39546336
39638902
-
SLC39A7
chr6
33200445
33204439
+
COA6
chr1
234373456
234385068
+
EEF2
chr19
3976056
3985463
-
ZNF529
chr19
36534774
36605276
-
PRRC2B
chr9
131373636
131500197
+
GAPDH
chr12
6534512
6538374
+
BTBD10
chr11
13388001
13463297
-
EIF4B
chr12
53006158
53042209
+
MT-CO1
chrMT
5904
7445
+
MT-ND1
chrMT
3307
4262
+
CCNK
chr14
99481169
99535044
+
CRTAP
chr3
33114014
33147773
+
DDX47
chr12
12813316
12829981
+
HSP90AA1
chr14
102080738
102139699
-
MT-CO3
chrMT
9207
9990
+
ACTR1A
chr10
102461881
102502712
-
HLA-B
chr6
31269491
31357188
-
EIF3E
chr8
108201216
108435333
-
BTG2
chr1
203305491
203309602
+
RPS7
chr2
3575260
3580920
+
P4HB
chr17
81843161
81860624
-
GNAI3
chr1
109548615
109600195
+
TRIR
chr19
12730640
12734684
-
ANAPC11
chr17
81890790
81900991
+
WBP11
chr12
14784582
14803486
-
MRPS7
chr17
75261674
75266376
+
ALAS1
chr3
52198086
52214327
+
ZNF189
chr9
101398873
101410660
+
miRNA targets:
miRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
hsa-miR-3136-3p
chr3
69048966
69048987
-
hsa-miR-7111-3p
chr6
35470558
35470579
+
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
MAPKAPK5-AS1
chr12
111839764
111842902
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.