Entry Detail


General Information

Database ID:exR0510817
RNA Name:ABTB2
RNA Type:mRNA
Chromosome:chr11
Starnd:-
Coordinate:
Start Site(bp):34150987End Site(bp):34358010
External Links:ENSG00000166016



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ACAA2
chr18
49782164
49813953
-
AL136454.1
chr1
192716132
192716653
+
ATE1
chr10
121740421
121928801
-
CEP104
chr1
3812086
3857214
-
CYP4X1
chr1
47023669
47050751
+
ECE1
chr1
21217247
21345572
-
EEF2
chr19
3976056
3985463
-
FAM118A
chr22
45308968
45341955
+
FASN
chr17
82078338
82098294
-
GAPDH
chr12
6534512
6538374
+
ID3
chr1
23557926
23559501
-
KRAS
chr12
25205246
25250936
-
NPAT
chr11
108157215
108222638
-
PDIA4
chr7
149003062
149028662
-
PHC3
chr3
170086732
170181749
-
PTTG1IP
chr21
44849585
44873903
-
RAB1B
chr11
66268590
66277492
+
RBBP4
chr1
32651142
32686211
+
RPL22
chr1
6185020
6209389
-
RPS18
chr6
33272075
33276511
+
RUSC1
chr1
155320894
155331114
+
SERP1
chr3
150541998
150603228
-
SHISA5
chr3
48467798
48504826
-
SRGN
chr10
69088103
69104805
+
SRP68
chr17
76038775
76072517
-
STAT6
chr12
57095408
57132139
-
TBC1D2B
chr15
77984036
78077724
-
TUBB
chr6
30720352
30725426
+
TWNK
chr10
100987367
100994403
+
ZFYVE9
chr1
52142094
52346686
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AP003392.4
chr11
119065263
119065677
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.