Entry Detail


General Information

Database ID:exR0510822
RNA Name:ACAD10
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):111686056End Site(bp):111757107
External Links:ENSG00000111271



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
NDUFA10
chr2
239892450
240025345
-
GPCPD1
chr20
5544439
5611006
-
IPP
chr1
45694324
45750653
-
MRM2
chr7
2234195
2242205
-
SLAMF6
chr1
160485030
160523262
-
MYH9
chr22
36281277
36388067
-
SLC52A2
chr8
144354135
144361272
+
CPT1C
chr19
49690898
49713731
+
PSMD11
chr17
32444379
32483319
+
HMGB2
chr4
173331376
173334432
-
SP110
chr2
230167293
230225729
-
CBX3
chr7
26201162
26213607
+
DNAJC25
chr9
111631334
111654351
+
PTP4A3
chr8
141391995
141432454
+
CMTR1
chr6
37433219
37482827
+
PLXNA1
chr3
126988594
127037392
+
ZBED4
chr22
49853844
49890080
+
ST8SIA1
chr12
22063773
22437041
-
ACTN1
chr14
68874143
68979440
-
UBE2Z
chr17
48908407
48929056
+
GRK2
chr11
67266473
67286556
+
DCTN2
chr12
57530102
57547331
-
FOXM1
chr12
2857681
2877155
-
MT-ND1
chrMT
3307
4262
+
VIPAS39
chr14
77426675
77457952
-
EPM2AIP1
chr3
36985043
36993131
-
ST6GAL1
chr3
186930502
187078553
+
TPGS2
chr18
36777647
36829216
-
AL132780.3
chr14
22946270
22982258
-
FSCN3
chr7
127591409
127602144
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.