Entry Detail


General Information

Database ID:exR0510827
RNA Name:ACADM
RNA Type:mRNA
Chromosome:chr1
Starnd:+
Coordinate:
Start Site(bp):75724347End Site(bp):75787575
External Links:ENSG00000117054



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
DBN1
chr5
177456608
177474401
-
HMGA1
chr6
34236873
34246231
+
ARID5A
chr2
96536743
96552634
+
RPN2
chr20
37178410
37241619
+
HACD3
chr15
65530418
65578349
+
ITGB3BP
chr1
63440770
63593721
-
HYOU1
chr11
119044188
119057227
-
SLC35G1
chr10
93893973
93956062
+
RBMXL1
chr1
88979456
88992960
-
DTX4
chr11
59171430
59208588
+
FOXN2
chr2
48314637
48379295
+
PNN
chr14
39175183
39183220
+
BUB1B
chr15
40161023
40221136
+
DDX39B
chr6
31530219
31542448
-
GDI2
chr10
5765223
5842132
-
FTL
chr19
48965309
48966879
+
PKM
chr15
72199029
72231822
-
SRRM1
chr1
24631716
24673281
+
EXOSC8
chr13
36998816
37009614
+
DHX8
chr17
43483865
43610338
+
TRPC4
chr13
37636636
37870425
-
POLDIP3
chr22
42583721
42614962
-
RPL30
chr8
98024851
98046469
-
COA7
chr1
52684449
52698347
-
DNMT3B
chr20
32762385
32809356
+
ATP6V1G2-DDX39B
chr6
31530219
31546608
-
RPS24
chr10
78033760
78056813
+
NR1H2
chr19
50329653
50383388
+
NCOA4
chr10
46005088
46030714
-
XPO1
chr2
61477849
61538626
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004812.2
chr12
120116907
120119000
+
AC009948.2
chr2
178548884
178550681
+
AC069287.1
chr11
112967
125927
-
AL831711.1
chr1
161433444
161440996
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.