Entry Detail


General Information

Database ID:exR0510828
RNA Name:ACADS
RNA Type:mRNA
Chromosome:chr12
Starnd:+
Coordinate:
Start Site(bp):120725774End Site(bp):120740008
External Links:ENSG00000122971



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC004832.3
chr22
30409255
30428990
+
AP002990.1
chr11
62559603
62591531
-
CD52
chr1
26317958
26320523
+
CHD4
chr12
6570082
6614524
-
CYSTM1
chr5
140175156
140282052
+
DNAJC5
chr20
63895126
63936031
+
EEF1G
chr11
62559596
62574086
-
EIF2B1
chr12
123620406
123633766
-
EIF3J
chr15
44537125
44563029
+
EIF5AL1
chr10
79512601
79516440
+
GPAT2
chr2
96021946
96039451
-
HNRNPA2B1
chr7
26173057
26201529
-
IMP3
chr15
75639085
75648706
-
LRRK1
chr15
100919327
101078257
+
MCM7
chr7
100092728
100101940
-
MLH1
chr3
36993350
37050846
+
MTFP1
chr22
30425623
30429054
+
PFKL
chr21
44300051
44327376
+
PIP4K2C
chr12
57591174
57603418
+
PPP2R1A
chr19
52190048
52229518
+
RPLP1
chr15
69452814
69456205
+
RPS3
chr11
75399515
75422280
+
SMAD7
chr18
48919853
48952052
-
STIM1
chr11
3854527
4093210
+
TBX3
chr12
114670255
114684175
-
TPI1
chr12
6867119
6870948
+
TUBB
chr6
30720352
30725426
+
UNC119B
chr12
120710458
120723640
+
VCP
chr9
35056064
35072627
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.