Entry Detail


General Information

Database ID:exR0510829
RNA Name:ACADSB
RNA Type:mRNA
Chromosome:chr10
Starnd:+
Coordinate:
Start Site(bp):123008979End Site(bp):123058290
External Links:ENSG00000196177



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
B2M
chr15
44711487
44718877
+
B4GAT1
chr11
66345374
66347629
-
BUB3
chr10
123154402
123170467
+
C11orf58
chr11
16613132
16758340
+
CCND2
chr12
4273762
4305353
+
COX18
chr4
73052362
73069755
-
DDX24
chr14
94048287
94081212
-
DHCR24
chr1
54849627
54887195
-
EIF4E
chr4
98871684
98930637
-
HLA-B
chr6
31269491
31357188
-
MCFD2
chr2
46901870
46941855
-
MICB
chr6
31494881
31511124
+
NCOR1
chr17
16029157
16218185
-
NFATC3
chr16
68084751
68229259
+
NOP53
chr19
47745546
47757058
+
POGK
chr1
166839447
166856344
+
POLE3
chr9
113407235
113410675
-
RFFL
chr17
35005990
35089319
-
TPT1
chr13
45333471
45341370
-
VMP1
chr17
59707192
59842255
+
YWHAE
chr17
1344275
1400222
-
YWHAQ
chr2
9583967
9630997
-
ZNF100
chr19
21722771
21767579
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.