Entry Detail


General Information

Database ID:exR0510830
RNA Name:ACADVL
RNA Type:mRNA
Chromosome:chr17
Starnd:+
Coordinate:
Start Site(bp):7217125End Site(bp):7225266
External Links:ENSG00000072778



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
VKORC1
chr16
31090842
31095980
-
EIF2S1
chr14
67360151
67386516
+
OAF
chr11
120211032
120230334
+
TXN2
chr22
36467046
36481640
-
LRRC8A
chr9
128882112
128918039
+
ALKBH4
chr7
102456238
102464863
-
IGF2BP2
chr3
185643739
185825056
-
TMED7
chr5
115613210
115632992
-
ZNF782
chr9
96816269
96875623
-
RRP1B
chr21
43659560
43696079
+
ERI3
chr1
44221070
44355260
-
RAN
chr12
130872037
130877678
+
PXDN
chr2
1631887
1744852
-
PLEKHG4B
chr5
92151
189972
+
B2M
chr15
44711487
44718877
+
RBM8A
chr1
145917714
145927678
-
ZNRF2
chr7
30284597
30367689
+
SLC29A1
chr6
44219553
44234142
+
CANX
chr5
179678628
179731641
+
ZFP36L1
chr14
68787660
68796253
-
RBM23
chr14
22893204
22919182
-
EMP3
chr19
48321509
48330553
+
WDSUB1
chr2
159235793
159286799
-
GSTP1
chr11
67583742
67586656
+
FAM102A
chr9
127940582
127980989
-
UQCRHL
chr1
15807169
15809348
-
CD70
chr19
6583183
6604103
-
GOPC
chr6
117560269
117602542
-
RIPOR1
chr16
67518418
67546788
+
POLDIP3
chr22
42583721
42614962
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AC098850.4
chr17
16788057
16816540
+
AD000090.1
chr19
35557956
35581954
+
PCAT14
chr22
23536881
23547797
+
STAG3L5P-PVRIG2P-PILRB
chr7
100336104
100367831
+
XIST
chrX
73820649
73852723
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.