Entry Detail


General Information

Database ID:exR0510833
RNA Name:ACAT1
RNA Type:mRNA
Chromosome:chr11
Starnd:+
Coordinate:
Start Site(bp):108116695End Site(bp):108147603
External Links:ENSG00000075239



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
ATP2A2
chr12
110280756
110351093
+
MTRNR2L8
chr11
10507894
10509186
-
TRIP10
chr19
6737925
6751530
+
NPEPPS
chr17
47522942
47623276
+
DAPK1
chr9
87497228
87708634
+
PSMB5
chr14
23016543
23035230
-
CCDC102A
chr16
57512181
57536571
-
FZD3
chr8
28494205
28574267
+
NCAM1
chr11
112961247
113278436
+
PRDX4
chrX
23664262
23686397
+
PSMD10
chrX
108084207
108091549
-
PGK1
chrX
77910739
78129295
+
HSP90AB1
chr6
44246166
44253888
+
NPIPB2
chr16
11927259
11976643
-
TXNRD1
chr12
104215779
104350307
+
MRPL47
chr3
179588285
179604649
-
AC010422.3
chr19
12643831
12648397
-
GHITM
chr10
84139509
84153568
+
POU3F3
chr2
104853287
104858574
+
RPS4X
chrX
72255679
72277248
-
DAP3
chr1
155687960
155739010
+
EEF1A1
chr6
73515750
73523797
-
GLI2
chr2
120735623
120992653
+
IER3IP1
chr18
47152834
47176364
-
RPLP1
chr15
69452814
69456205
+
ACTG1
chr17
81509971
81523847
-
IGFBP2
chr2
216632828
216664436
+
NUP205
chr7
135557917
135648757
+
ACTB
chr7
5527148
5563784
-
TXNDC16
chr14
52430596
52552522
-
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
MIR155HG
chr21
25561909
25575168
+
POLR2J4
chr7
43940895
44019175
-
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.