Entry Detail


General Information

Database ID:exR0510834
RNA Name:ACAT2
RNA Type:mRNA
Chromosome:chr6
Starnd:+
Coordinate:
Start Site(bp):159762045End Site(bp):159779112
External Links:ENSG00000120437



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
RIMS3
chr1
40620680
40665682
-
RPL13
chr16
89560657
89566828
+
ATP5MC2
chr12
53632726
53677408
-
TTF2
chr1
117060326
117107453
+
FAM83F
chr22
39994954
40043534
+
TMEM14C
chr6
10722915
10731129
+
PWP2
chr21
44107373
44131181
+
CINP
chr14
102341102
102362916
-
FKBP8
chr19
18531751
18544077
-
PFN1
chr17
4945652
4949061
-
HDAC11
chr3
13479724
13506424
+
RIOX1
chr14
73490933
73493394
+
HSF1
chr8
144291591
144314720
+
SLC7A3
chrX
70925579
70931125
-
RPS13
chr11
17074388
17077715
-
ALG12
chr22
49900229
49918438
-
SKIL
chr3
170357678
170396835
+
BTG1
chr12
92140278
92145846
-
FDPS
chr1
155308748
155320666
+
ZCCHC10
chr5
132996985
133026604
-
IFT27
chr22
36758202
36776256
-
SURF2
chr9
133356550
133361158
+
COX6B1
chr19
35648323
35658782
+
ZNF451
chr6
57086844
57170305
+
RPL30
chr8
98024851
98046469
-
MLYCD
chr16
83899115
83951445
+
HAUS4
chr14
22946228
22957161
-
RPL37
chr5
40825262
40835222
-
MTRNR2L11
chr1
237943724
237945275
-
KDM4A
chr1
43650149
43705518
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AD000090.1
chr19
35557956
35581954
+
AL158835.3
chr10
125707416
125749525
-
HCP5
chr6
31463170
31478936
+
PRNCR1
chr8
127079874
127092600
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.