Entry Detail


General Information

Database ID:exR0510838
RNA Name:ACBD6
RNA Type:mRNA
Chromosome:chr1
Starnd:-
Coordinate:
Start Site(bp):180269653End Site(bp):180502954
External Links:ENSG00000230124



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
TMEM187
chrX
153972754
153983194
+
SIGMAR1
chr9
34634722
34637809
-
COPS7A
chr12
6724014
6731875
+
SPTLC3
chr20
13008972
13169103
+
BLOC1S1
chr12
55716037
55720087
+
TOB2
chr22
41433494
41446801
-
ACAP3
chr1
1292390
1309609
-
AC011455.2
chr19
38915404
38949855
-
TUBA1A
chr12
49184795
49189080
-
GLTP
chr12
109850945
109880541
-
FBXO17
chr19
38941401
38975742
-
CMTM4
chr16
66614750
66696707
-
AC055811.2
chr17
17202649
17237185
-
PHACTR4
chr1
28369582
28500364
+
NUDT15
chr13
48037726
48047221
+
ADGRL1
chr19
14147743
14206187
-
RER1
chr1
2391775
2405442
+
EIF4H
chr7
74174245
74197101
+
MAFK
chr7
1530702
1543043
+
PLXNA3
chrX
154458281
154477779
+
TOMM40
chr19
44890569
44903689
+
HAUS1
chr18
46104378
46128333
+
INPP5A
chr10
132537787
132783480
+
FTL
chr19
48965309
48966879
+
HINFP
chr11
119121580
119136059
+
MT-CO2
chrMT
7586
8269
+
TUBB
chr6
30720352
30725426
+
SEH1L
chr18
12947133
12987536
+
VCP
chr9
35056064
35072627
-
B3GNT5
chr3
183253253
183298504
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:
lncRNA SymbolChromosomeStart Site(bp)End Site(bp)Strand
AL121992.1
chr1
15586136
15603626
-
AL121987.1
chr1
160062461
160080769
+
AL645608.2
chr1
911435
914948
+
MALAT1
chr11
65497688
65506516
+
SLC16A1-AS1
chr1
112956415
113047055
+
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.