Entry Detail


General Information

Database ID:exR0510842
RNA Name:ACD
RNA Type:mRNA
Chromosome:chr16
Starnd:-
Coordinate:
Start Site(bp):67657512End Site(bp):67660815
External Links:ENSG00000102977



Disease Information

Disease Name:Lactation
Disease Category:Other Diseases
MeSH ID:D007774
Type:Phenomena and Processes Category/Reproductive and Urinary Physiological Phenomena
Alias:Milk Secretion//Milk Secretions//Lactation, Prolonged//Lactations, Prolonged//Prolonged Lactation//Prolonged Lactations



Expression Detail

GEO ID:GSE36936
Description:Gene Expression in the Human Mammary Epithelium during Initiation of Lactation.
Experimental Design:Time Series
Case Disease Type:Lactation
Case Disease SubType:NA
Case Sample:12h post delivery
Control Sample:6h post delivery
Number of Case:7
Number of Control:7
Number of Samples:14





Regulatory Relationship

mRNA targets:
Gene SymbolChromosomeStart Site(bp)End Site(bp)Strand
DHX9
chr1
182839347
182887982
+
DGCR2
chr22
19036282
19122454
-
HSP90AB1
chr6
44246166
44253888
+
AP002990.1
chr11
62559603
62591531
-
ZNF23
chr16
71447597
71463095
-
DUSP3
chr17
43766125
43778977
-
EEF1G
chr11
62559596
62574086
-
SEC22C
chr3
42547969
42601080
-
SLC35B2
chr6
44254096
44257890
-
PPM1A
chr14
60245752
60299087
+
CDK16
chrX
47217860
47229997
+
MEPCE
chr7
100428790
100434118
+
FGFRL1
chr4
1009936
1026898
+
NAA10
chrX
153929225
153935080
-
MT-CO1
chrMT
5904
7445
+
ATP6V1D
chr14
67294371
67360265
-
EFTUD2
chr17
44849948
44899445
-
TFAM
chr10
58385345
58399220
+
RAF1
chr3
12583601
12664226
-
MARCKSL1
chr1
32333839
32336233
-
CNOT1
chr16
58519951
58629885
-
FSTL3
chr19
676392
683392
+
HNRNPD
chr4
82352498
82374503
-
PCBP2
chr12
53452102
53481162
+
TSPAN9
chr12
3077355
3286564
+
PSMA4
chr15
78540405
78552417
+
GCN1
chr12
120127202
120194715
-
COX14
chr12
50112082
50120457
+
GNAS
chr20
58839718
58911192
+
RPS6KA1
chr1
26529761
26575030
+
miRNA targets:NA
circRNA targets:NA
lncRNA targets:NA
Display:



Experiment Detail

GEO ID:NA
Sample Source:NA
Source Fraction:NA
Platform:NA
Method:NA
Num of detected RNA Type:NA
Num of detected RNAs of this Type:NA
Sample treatment protocol:NA
RNA Extract protocol:NA
RNA library preparation protocol:NA



Reference

PMID:22649065
Title:Gene regulation of UDP-galactose synthesis and transport: potential rate-limiting processes in initiation of milk production in humans
Author:Mohammad MA, Hadsell DL, Haymond MW.
Journal:Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E365-76.
Description:We have utilized our established model of the RNA isolated from breast milk fat globule from seven healthy, exclusively breastfeeding women from 6 h to 42 days following delivery to determine the temporal coordination of changes in gene expression in the carbohydrate metabolic processes emphasizing the lactose synthesis pathway in human mammary epithelial cell.